There are few things worse than having to avoid eating your favorite ice cream because you don’t want to experience the pain caused by sensitive teeth. That may soon be a thing of the past, with researchers developing a novel way of rebuilding lost tooth minerals, offering a long-term solution to…
In preclinical trials, participants received a dental lozenge the size of a cough drop, with a core of calcium and phosphate coated in a layer of peptide-infused flavoring.
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Further research is needed to investigate the permeability and chemical stability of the mineral layer to achieve an effective, easy-to-apply treatment for dentin hypersensitivity, including implementing the peptide-guided approach under in vivo conditions.
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Research article (Feb, 28, 2023): https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c01039