Hey trans fems!! I’ve had my doses for ages, but I’ve been too consumed with life to worry about trying them. I just got news that my chapter of life is going to be changing soon, and I really wanted to try them during my current stride. So I’ve decided that just for one day I’m going to give it a shot to see how it makes my brain feel, and I’m going to do a proper two week test run another time. What can I expect from the first day? Any things to be concerned about? Is it possible that this derails my productivity or something strange for the first day?


Won’t have immediate effects. It’s a slow process. These hormones don’t have a lot of direct effects on the body, they affect other hormones and other bodily functions. Even two weeks probably will have very little effect. You need several months for emotional changes and breast growth to start up.
Also are you just taking estradiol or also an androgen blocker. General guidance now is to avoid androgen blockers at first and test testosterone levels to see if your body slows production of them. Androgen blockers have side effects, but without them the changes may take more time. And if you use them, generally your body adapts and you can’t stop using them until maybe after bottom surgery. But you may have to use them if your body doesn’t switch from androgen to estrogen production as the primary on its own which can be caused by both genetic and/or environmental factors. For me I may actually need supplementation of testosterone, because even before my bottom surgery, and without anti-androgen I don’t have enough. You need a balance and it takes time for that to happen. I’m over a year and still not fully stabilized.
Anyway,