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She set a tone at the very start when she walked right into his space to shake his hand and made him almost pull back into himself in response. She was in charge and never stopped being in charge.
Harris also managed what neither Joe Biden nor Hillary Clinton nor any of the 2016 Republicans managed to do which is successfully bait Donald Trump and get under his skin. Within a few minutes Trump was visibly angry and not in a way that empowered him but in a way that made him lose focus, go down rabbit holes and generally go off onto damaging tangents. Spittle anger, not righteous anger, shall we say.
The moderators probably seemed like they were on her side, because they only fact checked trump. But we all know the reason for that is because most of what he said were lies.
And they conveniently ignore everything that doesn’t align with what they want to believe.